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Publications list

Links to articles in journal name

Manuscripts accepted or on bioRxiv:

Talice S, Barkan S, Snyder G, Ottolenghi A, Eliachar S, Ben-Romano R, Oisher S, Sharoni T, Lewandowska M, Sultan E, Goldstein O, Aharoni R, Hadad U, Davis C, Moran Y, Gershoni-Yahalom O, Traylor-Knowles N, Rosental B. "Candidate stem cell isolation and transplantation in Hexacorallia".  Cell Reports

Voskoboynik, Y., Glina, A., Kowarsky, M., Anselmi, C., Neff, N.F., Ishizuka, K.J., Palmeri, K.J., Rosental, B., Gordon, T., Quake, S.R. and Weissman, I.L., 2020. "Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas". bioRxiv.



Titus, J., Nayak, S., Sultan, E., Gershoni-Yahalom, O., Sinai, T., Zilberg, D. and Rosental, B., 2024. "Development and validation of a flow cytometry method to examine circulating leukocyte subpopulations in barramundi (Lates calcarifer)". Comparative Immunology Reports, 6, p.200142.

Clarke, D.N., Rose, N.H., De Meulenaere, E., Rosental, B., Pearse, J.S., Pearse, V.B. and Deheyn, D.D., 2024. "Fluorescent proteins generate a genetic color polymorphism and counteract oxidative stress in intertidal sea anemones". Proceedings of the National Academy of Sciences, 121(11), p.e2317017121.

Sudarshan, G., Weil, S., Manor, R., Goldstein, O., Sultan, E., Aflalo, E.D., Ofir, R., Zimin, S.V., Rosental, B. and Sagi, A., 2024. "Development of long-term primary cell culture of Macrobrachium rosenbergii: morphology, metabolic activity, and cell-cycle analysis". Frontiers in Marine Science, 10, p.1322744.


Sudarshan, G., Weil, S., Jasińska, W., Manor, R., Goldstein, O., Aflalo, E.D., Ofir, R., Zimin, S.V., Levy, T., Rosental, B. and Brotman, Y., 2023. "Correlation between metabolomic profile and proliferation of Macrobrachium rosenbergii primary embryonic cell culture". Frontiers in Marine Science.

Kuzmina, A., Korovin, D., Atari, N., Ottolenghi, A., Hu, P., Mandelboim, M., Rosental, B., Rosenberg, E., Diaz-Griffero, F. and Taube, R., 2023. "Changes within the P681 residue of spike dictate cell fusion and syncytia formation of Delta and Omicron variants of SARS-CoV-2 with no effects on neutralization or infectivity". Heliyon, 9(6).

Sudarshan, G., Weil, S., Rotem-Dai, N., Manor, R., Greenshpan, Y., Goldstein, O., Sharabi, O., Aflalo, E.D., Ofir, R., Rosental, B. and Gazit, R., 2023. "Enhanced proliferation in a prawn embryonic primary cell culture ectopically expressing mutated Ras". Frontiers in Marine Science, 9, p.1100971.

Malka, O., Malishev, R., Bersudsky, M., Rajendran, M., Krishnamohan, M., Shaik, J., Chamovitz, D. A., Tikhonov, E., Sultan, E., Koren, O., Apte, R. N., Rosental, B., Voronov, E., & Jelinek, R. (2023). Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation. Journal of innate immunity, 10.1159/000529782.



Traylor-Knowles, N., Browne, W. E., Mydlarz, L. D., Palmer, C. V., & Rosental, B. (2022). "Innate Immunity in Early Diverging Metazoans". Frontiers in immunology, 13, 816550.

Eliachar, S., Snyder, G.A., Barkan, S.K., Talice, S., Otolenghi, A., Jaimes-Becerra, A., Sharoni, T., Sultan, E., Hadad, U., Levy, O., Moran, Y., Gershoni-Yahalom, O., Traylor-Knowles, N., and Rosental, B.,  2022. "Heat stress increases immune cell function in Hexacorallia". Frontiers in Immunology, 13.

Vanni, V., Anselmi, C., Ballarin, L., Drago, L., Gasparini, F., Gordon, T., Peronato, A., Rosental, B., Rosner, A., Rinkevich, B. and Spagnuolo, A., 2022. Current Knowledge on Stem Cells in Ascidians. Advances in Aquatic Invertebrate Stem Cell Research; MDPI: Basel, Switzerland, pp.273-335.

Hall, R.N., Weill, U., Drees, L., Leal-Ortiz, S., Li, H., Khariton, M., Chai, C., Xue, Y., Rosental, B., Quake, S.R. and Alvarado, A.S., 2022. "Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection". Cell reports methods, p.100298.

Zlotnik, D., Rabinski, T., Halfon, A., Anzi, S., Plaschkes, I., Benyamini, H., Nevo, Y., Gershoni, O.Y., Rosental, B., Hershkovitz, E. and Ben-Zvi, A., 2022. "P450 oxidoreductase regulates barrier maturation by mediating retinoic acid metabolism in a model of the human BBB". Stem cell reports, 17(9), pp.2050-2063.

Traylor-Knowles N, Browne WE, Mydlarz LD, Palmer CV and Rosental B (2022) Editorial: "Innate Immunity in Early Diverging Metazoans". Front. Immunol


Kuzmina, A., Wattad, S., Khalaila, Y., Ottolenghi, A., Rosental, B., Engel, S., Rosenberg, E. and Taube, R., 2021. "SARS CoV-2 Delta variant exhibits enhanced infectivity and a minor decrease in neutralization sensitivity to convalescent or post-vaccination sera". Iscience, 24(12), p.103467.

Rotem-Dai, N., Weil, S., Greenshpan, Y., Abehsera, S., Manor, R., Ofir, R., Gazit, R., Rosental, B., Aflalo, E.D. and Sagi, A., 2021. "Lentiviral-Transduced Ectopic Expression of Androgenic Hormone in a Crustacean Hematopoietic Primary Cell Culture". Frontiers in Marine Science, 8, p.677679.

Yakovenko, I., Donnyo, A., Ioscovich, O., Rosental, B. and Oren, M., 2021. The Diverse Transformer (Trf) Protein Family in the Sea Urchin Paracentrotus lividus Acts through a Collaboration between Cellular and Humoral Immune Effector Arms. International Journal of Molecular Sciences, 22(13), p.6639.

Goldstein, O., Mandujano-Tinoco, E.A., Levy, T., Talice, S., Raveh, T., Gershoni-Yahalom, O., Voskoboynik, A. and Rosental, B., 2021. "Botryllus schlosseri as a Unique Colonial Chordate Model for the Study and Modulation of Innate Immune Activity". Marine Drugs, 19(8), p.454.

Mandujano-Tinoco, E.A., Sultan, E., Ottolenghi, A., Gershoni-Yahalom, O. and Rosental, B., 2021. "Evolution of Cellular Immunity Effector Cells; Perspective on Cytotoxic and Phagocytic Cellular Lineages". Cells, 10(8), p.1853.

Upton R, Banuelos A, Feng D, Biswas T, Kao K, McKenna K, Willingham S, Ho PY, Rosental B, Tal MC, Raveh T. "Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance". Proceedings of the National Academy of Sciences (PNAS). 2021 Jul 20;118(29).

Snyder GA, Eliachar S, Connelly MT, Talice S, Hadad U, Gershoni-Yahalom O, Browne WE, Palmer CV, Rosental B and Traylor-Knowles N (2021) "Functional Characterization of Hexacorallia Phagocytic Cells". Front. Immunol. 12:662803.

Ballarin L, Karahan A, Salvetti A, Rossi L, Manni L, Rinkevich B, Rosner A, Voskoboynik A, Rosental B, Canesi L, Anselmi C, Pinsino A, Tohumcu BE, Jemec Kokalj A, Dolar A, Novak S, Sugni M, Corsi I and Drobne D (2021) "Stem Cells and Innate Immunity in Aquatic Invertebrates: Bridging Two Seemingly Disparate Disciplines for New Discoveries in Biology". Front. Immunol. 12:688106.

Yakovenko I, Donnyo A, Ioscovich O, Rosental B, Oren M. "The Diverse Transformer (Trf) Protein Family in the Sea Urchin Paracentrotus lividus Acts through a Collaboration between Cellular and Humoral Immune Effector Arms". International Journal of Molecular Sciences. 2021 Jan;22(13):6639.

Kowarsky M, Anselmi C, Hotta K, Burighel P, Zaniolo G, Caicci F, Rosental B, Neff NF, Ishizuka KJ, Palmeri KJ, Okamoto J, Gordon T, Weissman IL, Quake SR, Manni L, Voskoboynik A. "Sexual and asexual development: two distinct programs producing the same tunicate". Cell Rep. 2021 Jan 26;34(4):108681. doi: 10.1016/j.celrep.2020.108681. PMID: 33503429.


Snyder, G. A., Browne, W. E., Traylor-Knowles, N., Rosental, B. "Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations". J. Vis. Exp. (159), e60446, doi:10.3791/60446 (2020).


Rosental B, Raveh T, Voskoboynik A, & Weissman I. L. (2020). "Evolutionary perspective on the hematopoietic system through a colonial chordate: allogeneic immunity and hematopoiesis". Current Opinion in Immunology, 62, 91-98.


Oren M, Rosental B, Agronin J, Podini D, Hawley T, and Smith CL. “Individual sea urchin coelomocytes undergo somatic immune gene ‎diversification.” Frontiers in Immunology. 2019, 10:1298. doi: 10.3389/fimmu.2019.01298.

Smith CL, Hawley T, Henson JH, Majeske AJ, Oren M, and Rosental B. “Methods for collection, handling, and analysis of sea urchin coelomocytes”. Methods Cell Biol. 2019 ;150:357-389.


Rosental B, Kowarsky MA, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okomoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, Neff NF, Nolan GP, Quake SR, Weissman IL, and Voskoboynik A. “Complex mammalian-like haematopoietic system found in a colonial chordate".  Nature. (2018)

Barkal AA, Weiskopf K, Kao KS, Gordon SR, Rosental B, Yiu YY, George BM, Markovic M, Ring NG, Tsai JM, McKenna KM, Ho PY, Cheng RZ, Chen JY, Barkal LJ, Ring AM, Weissman IL, Maute RL. “Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy." Nature Immunology.  2018, 19(1):76-84., doi: 10.1038/s41590-017-0004-z.


*Pavlov V, *Rosental B, Rowbotham I, Hansen AF, and Block BA. “Hydraulic control of tuna fins: a role for the lymphatic system in locomotion." Science. 2017, 21;357(6348):310-314.

*(Equal contributor to first author) got the cover of Science.

Rosental B, Kozhekbaeva Z, Fernhoff N, Tsai J, and Traylor-Knowles N. “Coral cell separation and isolation by Fluorescence-Activated Cell Sorting". BMC Cell Biology. 2017, 29;18(1):30.

This article was chosen to be featured the BMC Cell Biology.



Shemesh A, Kugel S, Steiner N, Yezersky M, Tirosh D, Edri A, Telsh O, Rosental B, Sheiner E, Rubin E, Campbell K, and Porgador A. "NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint." E-publication ahead of print Oncotarget. 2016, DOI: 10.18632/oncotarget.12292.


*Corey DM, *Rosental B, Kowarsky MA, Sinha R, Ishizuka KJ, Palmeri KJ, Quake SR, Voskoboynik A, and Weissman IL. “Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners" Proceedings of the National Academy of Sciences (PNAS). 2016, 113(23):6520-5.

*(Equal contributor to first author)


Shemesh A, Brusilovsky M, Hadad U, Telsh O, Edri A, Campbell K, Rubin E, Rosental B, and Porgador A. “Survival in acute myeloid leukemia is associated with NKp44 splice variants." Oncotarget, 2016, 31;7(22):32933-45.


Rosental B, Shemesh A, Mendelson M, Ryger L, Kodman Y, Levy J, Porgador A, and Broides A. “Evaluation of purified Natural Killer cell- function in Familial Hemophagocytic Lymphohistiocytosis". LymphoSign Journal, 2015, 2(4): 207-212, 10.



Shemesh A, Tirosh D, Sheiner E, Tirosh NB, Brusilovsky M, Segev R, Rosental B, and Porgador A. “First Trimester Pregnancy Loss and the Expression of NKp30 Isoforms in Maternal Blood and Placental Tissue". Frontiers in Immunology, 2014, 1;6:189.

Tal Y, Yaakobi S, Horovitz-Fried M, Safyon E, Rosental B, Porgador A, and Cohen C. “An NCR1-based chimeric antigen receptor endows T-cells with multiple anti-tumor specificities". Oncotarget. 2014 April; 5.  



Brusilovsky M, Cordoba M, Rosental B, Hershkovitz O, Andrake M, Pecherskaya A, Einarson M, Zhou Y, Braiman A, Campbell K, and Porgador A. “Genome-wide siRNA screen reveals a new cellular partner of KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses." Journal of Immunology. 2013, 15;191(10):5256-67.



Rosental B, Hadad U, Sinay R, Braiman A, Porgador A, and Pollack Y. “Dual fluorescent labeling of the human malaria causing agent Plasmodium Falciparum for the analysis of the ABC type transporter pfmdr2." Malaria Journal. 2012, 8;11(1):371.


Brusilovsky M, Rosental B, Yossef R, Appel M, and Porgador A. “Human NK cell recognition of target cells in the prism of natural cytotoxicity receptors and their ligands." Journal of Immunotoxicology. 2012 July; 9(3):267-74.        


Rosental B, Hadad U, Brusilovsky M, Campbell K, and Porgador A. “A novel mechanism for evasion of NK response by cancer cells: interaction of NKp44 and Proliferating Cell Nuclear Antigen." OncoImmunology. 2012, 1(4):572-574.


Mendelson M, Yossef R, Appel M, Zilka A, Hadad U, Afergan F, Rosental B, Engel S, Braiman A and Porgador A. “Dimerization of NKp46 receptor is essential for NKp46-mediated lysis: characterization of the dimerization site by epitope mapping." Journal of Immunology. 2012, 188 (12):6165-74.


*Edri-Brami M, *Rosental B, Hayoun D, Welt M, Buskila H, Wirguin I, Nefussy B, Drori V, Porgador A, and Lichtenstein R. “Glycans in Sera of Amyotrophic Lateral Sclerosis Patients and Their Involvement in Killing Neuronal Cells". PlosONE. 2012, 7(5):e35772.   

*(Equal contributor to first author)

Rosental B, Appel M, Yossef R, Hadad U, Brusilovsky M, and Porgador A. “The effect of chemotherapy/radiotherapy on cancerous pattern recognition by NK cells". Current Medicinal Chemistry, 2012, 19(12):1780-91.

This article was chosen to be featured in Global Medical Discovery Series.


Yossef R, Rosental B, Appel M, Hershkovitz O, and Porgador A. “Upregulation of MHC Class I Expression Following Dengue Virus Infection: The Mechanism at the Promoter Level." Expert Review of Anti-infective Therapy, 2012, 10(3):285-7.



Rosental B, Brusilovsky M, Hadad U, Oz D, Appel M, Afergan F, Yossef R, Rosenberg L, Aharoni A, Cerwenka A, Campbell K, Braiman A, and Porgador A. “Proliferating Cell Nuclear Antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44." Journal of Immunology, 2011, 187(11):5693-702.     

This article was chosen to be featured in MDLinx.



Zilka A, Mendelson M, Rosental B, Hershkovitz O, and Porgador A. "Generating NK cell receptor-Fc chimera proteins from 293T cells and considerations of appropriate glycosylation". Methods Molecular Biology. 2010, 612: 275-83.



*Hershkovitz O, *Rosental B, Rosenberg L, Navarro-Sanchez M, Jivov S, Zilka A, Gershoni-Yahalom O, Brient-Litzler E, Bedouelle H, Ho J, Campbell K, Rager-Zisman B, Desprès P, and Porgador A. “NKp44 receptor mediates interaction of the envelope glycoproteins from the West-Nile and dengue viruses with Natural Killer cells". Journal of Immunology, 2009, 183: 2610–2621.      

*(Equal contributor to first author)


*Hecht ML, *Rosental B, Horlacher T, Hershkovitz O, De Paz JL, Noti C, Schauer S, Porgador A, and Seeberger PH. “Natural cytotoxicity receptors NKp30, NKp44 and NKp46 bind to different heparan sulfate/heparin sequences". Journal of Proteome Research, 2009, 8(2):712-20. 

*(Equal contributor to first author)​

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